A Rock and a Hard Place: Chiseling Away at the Multiple Mechanisms of Aortic Stenosis.
Circulation. 2017;135(20):1951-1955 - PMID: 28507250 - PMCID: PMC5479353 - DOI: 10.1161/CIRCULATIONAHA.117.027776
Insulin dissociates the effects of Liver X Receptor on lipogenesis, endoplasmic reticulum stress and inflammation.
J Biol Chem. 2015;291(3):1115-1122 - PMID: 26511317 - PMCID: PMC4714195 - DOI: 10.1074/jbc.M115.668269
Genesis and growth of extracellular-vesicle-derived microcalcification in atherosclerotic plaques.
Discoidin Domain Receptor-1 Regulates Calcific Extracellular Vesicle Release in Vascular Smooth Muscle Cell Fibrocalcific Response via Transforming Growth Factor-β Signaling.
Arterioscler Thromb Vasc Biol. 2016;36(3):525-33 - PMID: 26800565 - PMCID: PMC4767541 - DOI: 10.1161/ATVBAHA.115.307009
Myocardial Infarction Alters Adaptation of the Tethered Mitral Valve.
J Am Coll Cardiol. 2016;67(3):275-87 - PMID: 26796392 - PMCID: PMC5099077 - DOI: 10.1016/j.jacc.2015.10.092
Extracellular vesicles in cardiovascular calcification: Expanding current paradigms.
Multiple apolipoprotein kinetics measured in human HDL by high resolution/accurate mass parallel reaction monitoring.
Sortilin mediates vascular calcification via its recruitment into extracellular vesicles.
3D Ultrasound: seeing is understanding-from imaging to pathophysiology to developing therapies in secondary MR.
Eur Heart J Cardiovasc Imaging. 2016;17(5):510-1 - PMID: 26976355 - PMCID: PMC4829123 - DOI: 10.1093/ehjci/jew029
Simulation of early calcific aortic valve disease in a 3D platform: A role for myofibroblast differentiation.
J Mol Cell Cardiol. 2016;94:13-20 - PMID: 26996755 - PMCID: PMC4906202 - DOI: 10.1016/j.yjmcc.2016.03.004
Zooming in on the genesis of atherosclerotic plaque microcalcifications.
Macrophages in Vascular Inflammation: Origins and Functions.
Curr Atheroscler Rep. 2016;18(6):34 - PMID: 27125207 - DOI: 10.1007/s11883-016-0585-2
Extracellular vesicles in cardiovascular disease: focus on vascular calcification.
J Physiol. 2016;594(11):2877-80
Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation.
Endophenotype Network Models: Common Core of Complex Diseases.
Extracellular vesicles in cardiovascular disease: focus on vascular calcification.
A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification.
Atherosclerosis. 2016;251:109-118 - PMID: 27318830 - PMCID: PMC4983246 - DOI: 10.1016/j.atherosclerosis.2016.06.011
Histopathological assessment of calcification and inflammation of calcific aortic valves from patients with and without diabetes mellitus.
Histol Histopathol. 2016;32(3):293-306 - PMID: 27353274 - PMCID: PMC5199639 - DOI: 10.14670/HH-11-797
Noninvasive Molecular Imaging of Disease Activity in Atherosclerosis.
Circ Res. 2016;119(2):330-40 - PMID: 27390335 - PMCID: PMC4939871 - DOI: 10.1161/CIRCRESAHA.116.307971
Valve-in-valve Medtronic CoreValve implantation into a degenerated transapical Ventor Embracer aortic valve bioprosthesis.
Clin Res Cardiol. 2015;104(10):908-10
Role of live/real time three-dimensional transesophageal echocardiography in the percutaneous epicardial closure of the left atrial appendage.
Echocardiography. 2012;29(10):1256-60
Regular exercise or changing diet does not influence aortic valve disease progression in LDLR deficient mice.
PLOS One. 2012;7(5):e37298 - PMCID: PMC3351435
Current Trends and Future Perspectives of State-of-the-Art Proteomics Technologies Applied to Cardiovascular Disease Research.
Circ J. 2016;80(8):1674-83 - PMID: 27430298 - DOI: 10.1253/circj.CJ-16-0499
Delta-Like Ligand 4-Notch Signaling in Macrophage Activation.
Arterioscler Thromb Vasc Biol. 2016;36(10):2038-47 - PMID: 27562914 - PMCID: PMC5033717 - DOI: 10.1161/ATVBAHA.116.306926
Adventitial MSC-like Cells Are Progenitors of Vascular Smooth Muscle Cells and Drive Vascular Calcification in Chronic Kidney Disease.
Cell Stem Cell. 2016;19(5):628-642 - PMID: 27618218 - PMCID: PMC5097006 - DOI: 10.1016/j.stem.2016.08.001
PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation.
CD45 Expression in Mitral Valve Endothelial Cells After Myocardial Infarction.
Circ Res. 2016;119(11):1215-1225 - PMID: 27750208 - PMCID: PMC5215059 - DOI: 10.1161/CIRCRESAHA.116.309598
Automation of PRM-dependent D3-Leu tracer enrichment in HDL to study the metabolism of apoA-I, LCAT and other apolipoproteins.
Quantification of Calcified Particles in Human Valve Tissue Reveals Asymmetry of Calcific Aortic Valve Disease Development.
Unbiased and targeted mass spectrometry for the HDL proteome.
Curr Opin Lipidol. 2016;28(1):68-77 - PMID: 28002079 - PMCID: PMC6211176 - DOI: 10.1097/MOL.0000000000000374
In vitro 3D model and miRNA drug delivery to target calcific aortic valve disease.
Giving Calcification Its Due: Recognition of a Diverse Disease: A First Attempt to Standardize the Field.
Circ Res. 2017;120(2):270-273 - PMID: 28104767 - PMCID: PMC5260841 - DOI: 10.1161/CIRCRESAHA.116.310060
Serum Sortilin Associates With Aortic Calcification and Cardiovascular Risk in Men.
Arterioscler Thromb Vasc Biol. 2017;37(5):1005-1011 - PMID: 28279970 - PMCID: PMC5407935 - DOI: 10.1161/ATVBAHA.116.308932
Comparative Histopathological Analysis of Mitral Valves in Barlow Disease and Fibroelastic Deficiency.
Semin Thorac Cardiovasc Surg. 2016;28(4):757-767
Interferon-γ Released by Activated CD8(+) T Lymphocytes Impairs the Calcium Resorption Potential of Osteoclasts in Calcified Human Aortic Valves.
Am J Pathol. 2017;187(6):1413-1425 - PMID: 28431214 - PMCID: PMC5455058 - DOI: 10.1016/j.ajpath.2017.02.012
Flow Perturbation Mediates Neutrophil Recruitment and Potentiates Endothelial Injury via TLR2 in Mice - Implications for Superficial Erosion.
Circ Res. 2017;121(1):31-42 - PMID: 28428204 - PMCID: PMC5488735 - DOI: 10.1161/CIRCRESAHA.117.310694
Comparative Histopathological Analysis of Mitral Valves in Barlow Disease and Fibroelastic Deficiency.
Semin Thorac Cardiovasc Surg. 2016;28(4):757-767 - PMID: 28417861 - DOI: 10.1053/j.semtcvs.2016.08.015
Dynamic Macrophages: Understanding Mechanisms of Activation as Guide to Therapy for Atherosclerotic Vascular Disease.
Engineering a 3D-Bioprinted Model of Human Heart Valve Disease Using Nanoindentation-Based Biomechanics.
Nanomaterials (Basel). 2018;8(5):ePub - PMID: 29751516 - PMCID: PMC5977310 - DOI: 10.3390/nano8050296
Transcriptional control of intestinal cholesterol absorption, adipose energy expenditure and lipid handling by Sortilin.
Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes.
Simulations of morphotype-dependent hemodynamics in non-dilated bicuspid aortic valve aortas.
J Biomech. 2016;50:63-70 - PMID: 27855987 - DOI: 10.1016/j.jbiomech.2016.11.024
Mechanobiology in Cardiovascular Disease Management: Potential Strategies and Current Needs.
Front Bioeng Biotechnol. 2016;4:79 - PMID: 27777927 - PMCID: PMC5056184 - DOI: 10.3389/fbioe.2016.00079
Bicuspid aortic valve hemodynamics does not promote remodeling in porcine aortic wall concavity.
Etiology of bicuspid aortic valve disease: Focus on hemodynamics.
World J Cardiol. 2014;6(12):1227-33 - PMID: 25548612 - PMCID: PMC4278157 - DOI: 10.4330/wjc.v6.i12.1227
Bicuspid aortic valve hemodynamics induces abnormal medial remodeling in the convexity of porcine ascending aortas.
Biomech Model Mechanobiol. 2014;13(6):1209-25 - PMID: 24599392 - DOI: 10.1007/s10237-014-0567-7
The Transcriptional Signature of Growth in Human Fetal Aortic Valve Development.
Ann Thorac Surg. 2018;106(6):1834-1840 - PMID: 30071238 - DOI: 10.1016/j.athoracsur.2018.06.034
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.
J Extracell Vesicles. 2018;7(1):1535750 - PMID: 30637094 - PMCID: PMC6322352 - DOI: 10.1080/20013078.2018.1535750
Cardiovascular calcification: artificial intelligence and big data accelerate mechanistic discovery.
Nat Rev Cardiol. 2018;16(5):261-274 - PMID: 30531869 - DOI: 10.1038/s41569-018-0123-8
Roles and Regulation of Extracellular Vesicles in Cardiovascular Mineral Metabolism.
Front Cardiovasc Med. 2018;5:187 - PMID: 30622949 - PMCID: PMC6308298 - DOI: 10.3389/fcvm.2018.00187
147

