Automation of PRM-dependent D3-Leu tracer enrichment in HDL to study the metabolism of apoA-I, LCAT and other apolipoproteins.
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Unbiased and targeted mass spectrometry for the HDL proteome.
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In vitro 3D model and miRNA drug delivery to target calcific aortic valve disease.
Giving Calcification Its Due: Recognition of a Diverse Disease: A First Attempt to Standardize the Field.
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Serum Sortilin Associates With Aortic Calcification and Cardiovascular Risk in Men.
Arterioscler Thromb Vasc Biol. 2017;37(5):1005-1011 - PMID: 28279970 - PMCID: PMC5407935 - DOI: 10.1161/ATVBAHA.116.308932
Comparative Histopathological Analysis of Mitral Valves in Barlow Disease and Fibroelastic Deficiency.
Semin Thorac Cardiovasc Surg. 2016;28(4):757-767
Interferon-γ Released by Activated CD8(+) T Lymphocytes Impairs the Calcium Resorption Potential of Osteoclasts in Calcified Human Aortic Valves.
Am J Pathol. 2017;187(6):1413-1425 - PMID: 28431214 - PMCID: PMC5455058 - DOI: 10.1016/j.ajpath.2017.02.012
Flow Perturbation Mediates Neutrophil Recruitment and Potentiates Endothelial Injury via TLR2 in Mice - Implications for Superficial Erosion.
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Comparative Histopathological Analysis of Mitral Valves in Barlow Disease and Fibroelastic Deficiency.
Semin Thorac Cardiovasc Surg. 2016;28(4):757-767 - PMID: 28417861 - DOI: 10.1053/j.semtcvs.2016.08.015
A Rock and a Hard Place: Chiseling Away at the Multiple Mechanisms of Aortic Stenosis.
Circulation. 2017;135(20):1951-1955 - PMID: 28507250 - PMCID: PMC5479353 - DOI: 10.1161/CIRCULATIONAHA.117.027776
Dynamin-Related Protein 1 Inhibition Attenuates Cardiovascular Calcification in the Presence of Oxidative Stress.
Circ Res. 2017;121(3):220-233 - PMID: 28607103 - PMCID: PMC5546003 - DOI: 10.1161/CIRCRESAHA.116.310293
Incidence, Predictors, and Outcome of Patients Developing Infective Endocarditis Following Transfemoral Transcatheter Aortic Valve Replacement.
J Am Coll Cardiol. 2016;67(24):2907-8
Interventional post-myocardial infarction ventricular septal defect closure: a systematic review of current evidence.
EuroIntervention. 2016;12(1):94-102
Macrophage Heterogeneity Complicates Reversal of Calcification in Cardiovascular Tissues.
Effect of Losartan on Mitral Valve Changes After Myocardial Infarction.
J Am Coll Cardiol. 2017;70(10):1232-1244 - PMID: 28859786 - PMCID: PMC5679094 - DOI: 10.1016/j.jacc.2017.07.734
New insights into mitral valve dystrophy: a Filamin-A genotype-phenotype and outcome study.
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Mitral Leaflet Changes Following Myocardial Infarction: Clinical Evidence for Maladaptive Valvular Remodeling.
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Calcific aortic valve stenosis: hard disease in the heart: A biomolecular approach towards diagnosis and treatment.
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Sortilin and Its Multiple Roles in Cardiovascular and Metabolic Diseases.
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Mitral Valve Adaptation to Isolated Annular Dilation: Insights Into the Mechanism of Atrial Functional Mitral Regurgitation.
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Extracellular Vesicles As Mediators of Cardiovascular Calcification.
Cathepsin S As an Inhibitor of Cardiovascular Inflammation and Calcification in Chronic Kidney Disease.
Dimerization of sortilin regulates its trafficking to extracellular vesicles.
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Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles.
Flow Preservation of Umbilical Vein for Autologous Shunt and Cardiovascular Reconstruction.
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Spatiotemporal Multi-omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease.
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Mitral Valve Adaptation: Can We Win the Race?
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Engineering a 3D-Bioprinted Model of Human Heart Valve Disease Using Nanoindentation-Based Biomechanics.
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Transcriptional control of intestinal cholesterol absorption, adipose energy expenditure and lipid handling by Sortilin.
Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes.
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Mechanobiology in Cardiovascular Disease Management: Potential Strategies and Current Needs.
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Bicuspid aortic valve hemodynamics does not promote remodeling in porcine aortic wall concavity.
Etiology of bicuspid aortic valve disease: Focus on hemodynamics.
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Bicuspid aortic valve hemodynamics induces abnormal medial remodeling in the convexity of porcine ascending aortas.
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The Transcriptional Signature of Growth in Human Fetal Aortic Valve Development.
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Dynamic Macrophages: Understanding Mechanisms of Activation as Guide to Therapy for Atherosclerotic Vascular Disease.
Sheep-Specific Immunohistochemical Panel for the Evaluation of Regenerative and Inflammatory Processes in Tissue-Engineered Heart Valves.
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Editorial: Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases.
Front Cardiovasc Med. 2018;5:133 - PMID: 30283791 - PMCID: PMC6157324 - DOI: 10.3389/fcvm.2018.00133
Context-enriched interactome powered by proteomics helps the identification of novel regulators of macrophage activation.
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Cardiovascular calcification: artificial intelligence and big data accelerate mechanistic discovery.
Nat Rev Cardiol. 2018;16(5):261-274 - PMID: 30531869 - DOI: 10.1038/s41569-018-0123-8
Roles and Regulation of Extracellular Vesicles in Cardiovascular Mineral Metabolism.
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Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.
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18F-Fluoride Signal Amplification Identifies Microcalcifications Associated With Atherosclerotic Plaque Instability in Positron Emission Tomography/Computed Tomography Images.
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Endothelial to Mesenchymal Transition in Cardiovascular Disease: JACC State-of-the-Art Review.
J Am Coll Cardiol. 2019;73(2):190-209 - PMID: 30654892 - PMCID: PMC6865825 - DOI: 10.1016/j.jacc.2018.09.089
Differential miRNA Loading Underpins Dual Harmful and Protective Roles for Extracellular Vesicles in Atherogenesis.
Circ Res. 2019;124(4):467-469 - PMID: 30763209 - PMCID: PMC6383776 - DOI: 10.1161/CIRCRESAHA.119.314596
After 50 Years of Heart Transplants: What Does the Next 50 Years Hold for Cardiovascular Medicine? A Perspective From the International Society for Applied Cardiovascular Biology.
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